Authors - Alka Beniwal, Trishna Paul, Mukesh Kumar Rohil Abstract - In the rapidly changing landscape of daily life, medical imaging stands out as a significant and novel component, significantly impacting healthcare practices. The efficiency of medical imaging processes is pivotal, and within this realm, accurate image registration emerges as a key contributor. Despite its recognized importance, existing pipelines lack a definitive and well-defined structure tailored to the specific requirements of medical imaging. This paper exclusively directs its focus toward addressing this gap by thoroughly examining and redefining the image registration pipeline within the context of medical imaging. The objective is to enhance the efficiency of medical imaging procedures by establishing a tailored and comprehensive pipeline that aligns seamlessly with the unique demands of this critical domain. We also analyzed the different application areas of image registration in medical imaging with their benefits, challenges, and future directions.